When performed at an experienced fertility clinic with well trained laboratory technicians, PGD, is reported to be 99.9% effective in selecting genders. This is because the sex chromosomes of the embryo are examined and the XY (male) or XX (female) chromosomes are “seen” or identified with the florescence. The science has been proven and replicated at fertility clinics and in laboratories around the globe for about 30 years.
However, in looking at the overall process, another important question arises: Does a PGD cycle (IVF and PGD combined) work as effectively as IVF cycles alone, in terms of pregnancy outcomes? At HRC Fertility, pregnancy and implantation rates are the same whether a couple does only IVF, IVF with PGD, or IVF with PGD and MicroSort. If the clinic you work with is not as experienced with PGD, the cell extraction may not be as precise and skilled, and those embryos may be somewhat weakened, some believe, and not as likely to make it through the lab process and uterine implantation. So for the best chance at success, it’s important to work with a clinic with a proven reputation for PGD.
PGD is 99.9 % effective for gender selection. The reason that IVF-PGD is not 100% effective in gender selection is that in a miniscule amount of cases, when the single cell is removed from an embryo and screened, the embryologist may find no “signal” when in fact one should appear. This is quite rare, however.